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Shares clinical and pathological features of other dementias that may occur during the course of Parkinson’s disease and other neurological conditions. Pathologically, it is characterized by abnormal aggregation of, so called α-synuclein synaptic protein as ‘Lewy bodies’ in neurons associated with cerebral atrophy.
Cerebral atrophy is the term used to describe decrease of brain volume. This decrease brain volume is caused by a loss of brain tissue that occurs in everyone as a natural part of the aging process.